Mauricio Pochettino will try to make changes to his back four for the visit of Sean Dyche's side
The Spurs defender recovered from his early mistake to make what would prove to be a key block in the second half
The 21-year-old signed a new five-year deal with Spurs on Monday and will now start away to Barcelona
The 31-year-old will be expected to play a crucial role for Spurs at the Camp Nou on Tuesday
The Argentine defender has recently forced his way into Mauricio Pochettino's starting XI
Spurs will be without Jan Vertonghen, Davinson Sanchez, Victor Wanyama, Mousa Demble and Erik Lamela for the visit of Southampton
Arsenal are expected to make up to ten changes against Spurs for the 195th North London at the Emirates on Sunday afternoon.
Mauricio Pochettino must decide whether Jan Vertonghen is ready to play back-to-back games so soon after his hamstring injury
Danny Rose is also back in training for Tottenham Hotspur ahead of Wednesday's European clash with Inter Milan
Mauricio Pochettino accepts he is pushing his Tottenham squad to the limit as he counts of the cost of their World Cup exploits.
Tottenham manager Mauricio Pochettino says the club is working hard to get Christian Eriksen to commit his future to the club.
Premier League: Crystal Palace 0 Tottenham Hotspur 1
Tottenham Hotspur manager Mauricio Pochettino understands fans frustration as they jeered in the 62nd minute when he brought off Lucas Moura in their 2-1 Champions League win against PSV.
Spurs have received criticism for a lack of depth, but Mauricio Pochettino used 22 different players in the last two games and most impressed
Premier League: Wolverhampton Wanderers 2 Tottenham Hotspur 3
Spurs conceded early against Manchester City, but Argentinian Pochettino was impressed with their response
Erik Lamela fired over for Tottenham Hotspur with 10 minutes left and Man City boss Pep Guardiola blamed the pitch for the miss
While individuals could be blamed for Tottenham's struggles in Europe, collectively the team have not been good enough
A look at how some of Tottenham Hotspur's players fared while on international duty over the weekend
A look at how some of Tottenham Hotspur's players fared while on international duty this week
The Tottenham Hotspur forward discusses the upcoming UEFA Nations League games and Harry Winks' inclusion in the England squad
The Lilywhites are joint-bottom with no points while Barcelona and Inter Milan both have six each after two games in Group B
Champions League Group B: Tottenham Hotspur 2 Barcelona 4
The Lilywhites will be without Aurier, Vertonghen, Dembele, Alli and Eriksen for this week's Champions League Group B fixture
Premier League: Huddersfield Town 0 Tottenham Hotspur 2
Richard and Alan Myers look back through their history, from their founding in the Georgian era as rag recyclers to where they are now, selling mid-range carpets to the domestic market
Streathers Solicitors, with a number of offices across north London, has a team of highly experienced solicitors who offer a range of private client services.
St Albans' award-winning Gabriel Square development offers Londoners the chance to buy a luxury home with an easy commute to the capital
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